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‘200,000 living human neurons’ on a microchip demonstrated playing Doom — Cortical Labs CL1 video shows the gameplay and explains how the neurons learn the game

| 2 Min Read
Australia’s Cortical Labs has demonstrated its 'body in a box' CL1 biological computer playing Doom.

‘200,000 living human neurons’ on a microchip demonstrated playing Doom — Cortical Labs CL1 video shows the gameplay and explains how the neurons learn the game

Cortical Labs CL1
(Image credit: Cortical Labs)

Australia’s Cortical Labs has demonstrated its 'body in a box' CL1 biological computer playing Doom. A video showing the Doom gameplay, and explaining the processes behind this feat was shared by the research and development team. In the video intro, it is claimed that “around 200,000 living human neurons on a microchip” were used to power the seminal FPS action.

Living Human Brain Cells Play DOOM on a CL1 - YouTube Living Human Brain Cells Play DOOM on a CL1 - YouTube
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We reported on the Cortical Labs CL1 launch last year. The biotech company behind “the world’s first code deployable biological computer” was very bullish about their combination of human brain cells with traditional silicon-based computing. Shipments of CL1 computers were scheduled for June of the same year.

Previously, the CL1 development team had demonstrated the neurons playing the pioneering arcade game Pong, but internet users bombarded Cortical Labs with requests for Doom (of course). Now, Doom has been demonstrated being played by the mass of neurons.

“Doom was much more complex,” explained Dr. Brett Kagan in the video. Its 3D labyrinths, enemies, weapons, etc., make it several degrees more advanced than Pong. This complexity inspired the ‘Cortical Cloud’ for training more complex tasks.

“Together with one of our collaborators, an independent researcher named Sean Cole, we coded the first working version of Doom using the Cortical Labs API, and running on a CL1,” said Dr. Alon Loeffler of c, who presented this demo video. Kagan added that the demo showed “adaptive real-time goal-directed learning” in action.

Company CTO David Hogan explains that Sean Cole managed to pipe the “video feed from the game into patterns of electrical stimulation” and, in that way, the neurons could feel the action. So, for example, if the neurons fire in a specific learned pattern, the Doom guy shoots, and another pattern will prompt him to move position. This way, the brain cells can find enemies, shoot them, and then progress.

Not an eSports champion - yet

This is impressive to see, but “Is it an eSports champion? Absolutely not,” states Kagan, employing some rhetoric. Importantly, though, “they are learning,” and feedback for the right and wrong actions needs to be refined. Nevertheless, Cortical Labs is happy it has “solved the interface problem” to interact with the brain cells in real-time, and then train them and shape their behavior. This is why the CL1 was designed. And it is hoped the CL1 will be able to soon excel at Doom gaming, and then take on ever-increasingly complex tasks.

The video ends with a call to developers and researchers to come and interact with the open Cortical Labs CL1 API – to see what they can build. “The neurons are ready.”

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Mark Tyson
News Editor

Mark Tyson is a news editor at Tom's Hardware. He enjoys covering the full breadth of PC tech; from business and semiconductor design to products approaching the edge of reason.

  • -Fran-
    This is interesting, but I have to ponder: isn't the whole point of making machines not biological about removing the fragility (as much as possible) of humans? Did they quote a failure rate for their prototypes?

    I say this, because to my understanding neurons are very fragile in the human body (hence why whacking someone in the head is not a good thing). Humans compensate, somewhat, by having quite a lot of them: ~85000 million with a quick search.

    Still, it doesn't take away the amazingness of it. I look forward to the medical applications of this.

    Regards.
    Reply
  • Spuwho
    They aren't recreating the biological neurons physically, they are reproducing them digitally. So the "hit in the head" argument is not quite analogous. They are attempting to impress human engrams that are based on bio-neural pathways onto silicon. By playing Doom, they are baselining the capabilities of their work. Technically they could attempt to recreate any mammal since they all use bio-neural driven brain processing, but we haven't developed ways to test them because humans don't know how all mammals think. What is deduced, what is experiential, and what is instinctual.
    Reply
  • -Fran-
    Spuwho said:
    They aren't recreating the biological neurons physically, they are reproducing them digitally. So the "hit in the head" argument is not quite analogous. They are attempting to impress human engrams that are based on bio-neural pathways onto silicon. By playing Doom, they are baselining the capabilities of their work. Technically they could attempt to recreate any mammal since they all use bio-neural driven brain processing, but we haven't developed ways to test them because humans don't know how all mammals think. What is deduced, what is experiential, and what is instinctual.
    Thanks for the clarification. Very badly named tech then :D

    Regards.
    Reply
  • patriotpa
    Since when is it legal to play with human brain tissue?
    Reply
  • 80251
    Spuwho said:
    They aren't recreating the biological neurons physically, they are reproducing them digitally. So the "hit in the head" argument is not quite analogous. They are attempting to impress human engrams that are based on bio-neural pathways onto silicon. By playing Doom, they are baselining the capabilities of their work. Technically they could attempt to recreate any mammal since they all use bio-neural driven brain processing, but we haven't developed ways to test them because humans don't know how all mammals think. What is deduced, what is experiential, and what is instinctual.
    So they aren't "living neurons" at all, because they're not alive.

    I have to admit I was curious as to how they would keep biological cells alive in a silicon substrate.
    Reply
  • bit_user
    Spuwho said:
    They aren't recreating the biological neurons physically, they are reproducing them digitally.
    No, this is incorrect. The article is pretty explicit that these are biological neurons. If there was any doubt, the article links to a prior piece which explains more about the setup.
    https://www.tomshardware.com/tech-industry/worlds-first-body-in-a-box-biological-computer-uses-human-brain-cells-with-silicon-based-computing
    You can also click through the image carousel to see a few other pics:

    FWIW, I doubt the brain organoid is being fed raw pixel data. I think it must be preprocessed in some way. It's not nearly enough neurons to perform simple vision tasks.
    Reply
  • bit_user
    80251 said:
    So they aren't "living neurons" at all, because they're not alive.

    I have to admit I was curious as to how they would keep biological cells alive in a silicon substrate.
    Their website says "Real neurons are cultivated inside a nutrient rich solution, supplying them with everything they need to be healthy." !
    https://corticallabs.com/cl1.html
    Did it ever occur to you or @-Fran- to go back and check the article, when somebody (esp. with no sources or references) contradicts it?
    Reply
  • bit_user
    patriotpa said:
    Since when is it legal to play with human brain tissue?
    A human brain has about 90 billion neurons. This has 200k. That's almost a 6-order-of-magnitude difference!

    So, it's definitely not thinking. It's just on par with something like a simple insect.
    Reply
  • -Fran-
    bit_user said:
    Their website says "Real neurons are cultivated inside a nutrient rich solution, supplying them with everything they need to be healthy." !
    https://corticallabs.com/cl1.html
    Did it ever occur to you or @-Fran- to go back and check the article, when somebody (esp. with no sources or references) contradicts it?
    It did, but I'm lazy like that.

    Plus, I know you're around :P

    Regards.
    Reply
  • 80251
    Neurons can live for 90 years. I'd like to see proof that this biological device can do anything useful and for $35k they'll need some independent proof to convince me.
    Reply

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